PMDD or premenstrual dysphoric disorder, refers to a condition in which women and AFAB individuals of reproductive age have severe emotional symptoms, like depression, anxiety, mood swings, anger, or even thoughts of suicide, but these symptoms ONLY happen the 1-2 weeks before their menstrual period starts. So the symptoms look like a severe mood disorder, but they are only present in that premenstrual window.
We know that PMDD is caused by an abnormal brain reaction to normal changes in hormones across the cycle. HORMONE LEVELS ARE NORMAL IN PMDD, but the brain cannot adapt to the normal monthly changes for an unknown reason.
Updated 22 December, 2018 by Tory Eisenlohr-Moul, PhD