The treatment of PMDD is based on several factors. These factors include the primary PMDD target symptoms to be treated; a woman’s previous response to certain medications; the current medical conditions that she has; and the other medications she is currently taking.  For some women (especially those who do not respond to first-line treatments for PMDD), mood stabilizers (many of which can  also be called antidopaminergic medications) are very helpful in reducing the symptoms of mood lability, agitation, irritability, and the profound distress that occurs in the luteal phase of the menstrual cycle.  Talk to your doctor about treatment options that might be appropriate for you.
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-Gioia Guerrieri, DO, February 25, 2019