IAPMD

PMDD is NOT thought to be caused by a deficit in the levels of hormones<b> (such as progesterone or estradiol), but instead, it is thought to be an <a href="https://pubmed.ncbi.nlm.nih.gov/28427285/" target="_blank" rel="nofollow noopener noreferrer">abnormal response in the brain to fluctuating levels of hormones</a> across the menstrual cycle (specifically the luteal phase of the cycle) </b>

<a href="https://iapmd.org/clinical-advisory-board" target="_blank" rel="nofollow noopener noreferrer">Liisa Hantsoo, Ph.D</a>. Clinical Psychologist &amp; Assistant Professor. 

Also read: <a href="https://faq.iapmd.org/en/articles/2608631-is-pmdd-caused-by-a-hormone-imbalance" target="_blank" rel="nofollow noopener noreferrer">Is PMDD caused by a hormone imbalance? </a>

Is PMDD the same as luteal phase progesterone deficit?

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PMDD is NOT thought to be caused by a deficit in the levels of hormones (such as progesterone or estradiol), but instead, it is thought to be an abnormal response in the brain to fluctuating levels of hormones across the menstrual cycle (specifically the luteal phase of the cycle)